Trimethoprim-sulphamethoxazole for the treatment of Wegener's granulomatosis

Treatment of chancroid. A comparison of sulphamethoxazole and trimethoprim-sulphamethoxazole.

Since sulphonamides are no longer predictably effective in the treatment of chancroid the combination of trimethoprim-sulphamethoxazole (TMP-SMX) was evaluated to identify other effective regimens. One hundred and nine patients with genital ulcers (75 men and 34 women) seen at the Special Treatment Clinic in Nairobi, Kenya, were randomly assigned to treatment with a seven day course of either s...

Sulphamethoxazole-trimethoprim in the treatment of gonorrhoea.

SELECTION OF PATIENTS All patients who attended the Plymouth clinic during that period and from whom smears and cultures yielded gonococci were included in the trial with the following exceptions: (i) Pregnant women (ii) Known prostitutes (iii) Men with gonococcal proctitis (iv) Patients who had defaulted on previous occasions (v) Patients who would be unable to attend for regular follow-up. A ...

ENT manifestations of Wegeners granulomatosis.

Wegeners granulomatosis is a necrotizing granulomatous vasculitis with multisystemic involvement. We present two cases of Wegener's presenting with otological manifestations as the first symptom. These symptoms are subtle and diagnosis may be easily overlooked. Hence a high index of suspicion is required. Early diagnosis and treatment goes a long way in improving the outcomes and in preventing ...

Trimethoprim-sulphamethoxazole (Septrin) in the treatment of rectal gonorrhoea.

The recent increase in some parts of London of syphilis acquired homosexually (Lancet, 1964; Brit. med. J7., 1967) has indicated that a drug of nontreponemicidal properties is to be preferred in the treatment of gonococcal proctitis in homosexual men. Septrin was considered as a potentially useful remedy in these circumstances. Though taken orally and so subject to error or misuse, it needs be ...

Treatment of Salmonella paratyphi A osteomyelitis with trimethoprim-sulphamethoxazole.